SARS-CoV-2 Spike glycoprotein Receptor Binding Domain (SCoV2-RBD)

SARS-CoV-2 recombinant Spike glycoprotein Receptor Binding Domain (SCoV2-RBD) expressed as secreted protein in mammalian cells. It was purified from culture medium under native (non-denaturing) conditions using convenient chromatographic techniques. Five different products are available:

 

Note: The same protein from different cell lines is not identical in respect of glycosylation. Protein from CHO cells is glycosylated at lesser extent than analogous product from HEK293 cells. SCoV2-RBD secreted from either CHO or HEK cells showed similar results in ELISA with COVID-19 positive and negative human sera.