Based on the experience working with yeast expression systems we provide contract synthesis service for any recombinant protein of interest in the yeast cells.
BALTYMAS offers synthesis of recombinant proteins in yeast Saccharomyces cerevisiae and Pichia pastoris expression systems. Both intracellular and secreted expression options may be used. Laboratory scale expression service includes cloning of the gene of interest into yeast expression vectors, yeast cell transformation, growing and induction of yeast transformant culture followed by expression analysis and protein purification.
Besides conventional Saccharomyces cerevisiae and Pichia pastoris expression systems, there is also opportunity to try unique humanized yeast expression system, especially for secreted recombinant proteins. This system contains Saccharomyces cerevisiae cell lines expressing several human chaperones or other protein maturation assistants that function at different stages of cell secretion pathway. In some cases these protein folding or transfer assistants may improve the expression of complex secreted recombinant proteins in yeast.
Fast expression screening to identify suitable yeast strain and optimal conditions for expression could be performed at moderate price.